Sebastian Mueller, MD, PhD

Professor of Medicine,

Department of Medicine, 

Salem Medical Center

University of Heidelberg

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Prof. Sebastian Mueller, M.D., Ph.D.

Vice Head. Department of Medicine (Gastroenterology, Hepatology), Salem Medical Center and

Co-Director, Center for Alcohol Research, University of Heidelberg

ESBRA President

Zeppelinstraße 11 – 33

69121 Heidelberg, Germany

contact:

NEWS 

• DFG Grant to Vanessa Rausch und Sebastian Mueller, RA 2677/1-1 'Mechanisms of cancerogenic iron accumulation in alcoholic liver disease (ALD)'. Start: Summer 2015

• Novel funding on non-invasive assessment of liver iron by room-temperature susceptometry by the Dietmar-Hopp Foundation. Starting late 2015.

• Member of the genome-wide case-control study on "genetic risk factors for alcoholic cirrhosis" 2015 ongoing

• Webinar in 11th MAy 2016 in Paris on alcoholic liver disease and non-invasive fibrosis screening (Youtube link 60 min)

• Novel DFG Grant to Sebastian Mueller, MU 1373/9-1 on a fundamentally novel concept of liver cirrhosis (Mechanisms of sinusoidal pressure-induced liver fibrosis). Start January 2017. for information see also here and new hypothesis paper in WJG 2016.

• Sebastian Mueller elected as the new ESBRA president 2017-2021

• Novel grant from the Dietmar-Hopp foundation granted to Sebastian Mueller on "Longterm survival and alcohol consumption" 2018-2020 

Welcome to our Research Homepage!  

Our research group is located both at the Department of Medicine at  Salem Medical Center and the Center for Alcohol Research at the University of Heidelberg. The basic research facilities are located at the Theoretikum of the University of Heidelberg. 

Addresses:

Theoretikum

Im Neuenheimer Feld 365 1. OG

69120 Heidelberg

Our long term goals are 

• to better understand underlying molecular mechanisms of liver diseases

• to improve diagnosis and therapy of liver diseases 

Actual translational research topics focus on 

• liver diseases

• alcoholic liver disease

• cancer (hepatocellular and colorectal cancer)

• non-invasive diagnosis of liver fibrosis, fatty liver and hepatic iron overload

• fatty liver and steatohepatitis

• non-invasive detection of liver iron

• iron overload disorders

• liver stiffness 

Actual basic research topics are related to

• molecular mechanisms of oxidative stress 

• redox-regulation

• detection of reactive oxygen species

• novel models for oxidative stress and hypoxia

• inflammation and iron homeastasis 

• mechanisms of alcohol-mediated cancerogenesis

• biomechanics and extracellular matrix (fibrosis and cirrhosis)

Our work is presently funded by the DFG, NIH, the Dietmar-Hopp Foundation and the Manfred-Lautenschläger Foundation.