Sebastian Mueller, MD, PhD

Professor of Medicine,

CAR, University of Heidelberg 

VISCERA AG Bauchmedizin Bern 

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 Lab members  (more about the clinical study team can be found here)

Johannes Müller, (2014-2026), IT, Statistics, physicist since 2014 , iron sensing by susceptometry, geneticsShami Alquzi, since 2018, MD fellow, pharmacological modulation of liver stiffness

Shuai Lan, MD fellow, since 2008 , critical flicker fusion frequency in ALD

Sijuan Li, MD-PhD fellow since 5 2022 

Xiang Gao, MD-PhD fellow since 1 2023 (in cooperation with Prof. S. Immenschuh, Hannover) 

Yan Jin , MD-PhD fellow since 1 2023 (in cooperation with Prof. S. Immenschuh, Hannover)

Huanran Yu, MD-PhD fellow since 2022 (in cooperation with Prof. S. Chokshi and Dr. Antonio Riva, Institute of Hepatology, London)

Qian Chaosi, MD-PhD fellow since 2024 (in cooperation with Prof. Songqing He, Guangxi Medical University, Nanning, VR China)

Guoqing Ouyang, MD-PhD fellow since 2024 (in cooperation with Prof. Songqing He, Guangxi Medical University, Nanning, VR China)

Guoqing Ouyang, Johannes Müller, Sijuan Li, Qian Chaosi, and Sebastian Mueller, at ESBRA Brussels 2025

January 2023: Yufang Xie, Xiang Gao, Yan Jin, Chaowen Zheng, Sijuan Li, Sebastian Mueller, 

Sandra Schramm, Huanran Yu, Johannes Mueller

Heidelberg March 2019 

Second row from left: Linna Yu, Ines Silva, Vanessa Rausch, Johannes Mueller, Faiza Faraz

First row from left: Shiin Wang, Sebastian Mueller, Omar Elshaarawy, Tessa Peccerella, Cheng Chen

Salem Medical Center 2018 (from left): Sebastian Mueller, VAnessa Rausch, Sandra Krienke, Julia Mutzek, Johannes Mueller, Gustavo Fornazori, Omar Elsharaawy

Cooperation on µFibroscan 2014 with Dr. Laurent Sandrin (Echosens, Paris) in 2014 (from left): Hanna Raisi; Laurent Sandrin, Vanessa Rausch, Tessa Peccerella, Sebastian Mueller, Johannes Mueller, Felix Piecha	S. Ottinger, T. Peccerella (2012)	S. Mueller, V. Rausch, 2014, EASL

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Former lab members (since 2007)

Gunda Millonig, MD, Ass. Prof. (2007-2012) 

Tessa Peccerella, PhD, technician and lab coordinator (2010-2020) 

Sabine Ottinger, PhD biologist (2011-2012)

Christian Dietrich, MD student, (2011-2014), Liver stiffness and heart failure, 2014, cum laude

Stephan Fichtner, study coordinator (2012-2013)

Vanessa Rausch,  PhD (2013-2019), biologist, postdoctoral fellow,  group leader since 2013, DFG Grant RA 2677/1-1 'Mechanisms of cancerogenic iron accumulation in alcoholic liver disease (ALD)'

Felix Piecha, graduate student, 2017, (2013-2017), Pharmacological modulation of liver stiffness in small animal models, magna cum laude

Ines Silva, PhD student (2014-2019)

Julia Mutzek, study coordinator (2014-2018)

Antje Hagedorn-Dambuk, study nurse (2014-2017)

Ulrike Nattenüller, study nurse (2014-2016)

Johannes Müller, physicist(2014-2026), IT, Statistics,  iron sensing by susceptometry, genetics   

Jutta Mohr, technician (2015-2018)

Hanna Raisi, MD clinical fellow, (2015-2020), cum laude 

Sandra Schramm, study coordinator (2017-2023)

Tomomi Otani, Clinical Research Associate (2017-2018)

Omar Elshaarawy, MD, (2018-2020), magna cum laude 

Shijin Wang, MD-PhD fellow, (2019-2022), BMP-mediated iron signaling, magna cum laude

Chen Cheng, PhD fellow, Dr. sc. hum.  (2019-2022), Modulation of autophagy by alcohol and peroxide, magna cum laude

Linna Yu, MD-PhD fellow, (2019-2022), iron modulation of hepcidin signaling, magna cum laude 

Chaowen Zheng, MD-PhD, (2022-2025), Direct red blood cell ingestion by hepatocytes (efferocytosis),  magna cum laude

Sijuan Li (2022-2025), MD-PhD, Ethanol-mediated phosphatidylserine-dependent clearance of red blood cells by liver sinusoidal endothelial cells (efferocytosis)

Yufang Xie, MD-PhD fellow 2023

Guoqing Ouyang, MD-PhD,  ( 2024-2026),  Stage-dependent genetic effects explain inconsistent associations with mortality in alcohol-related liver disease

Former visiting scientists

Dr. Hua Qin, (2009-2010), Tongji Hospital affiliated to Tongji Medical College, Wuhan, China  

Dr. Esteban Durango, MD (2009-2011), Ecuador

Dr. Toni Sureda, (2003) Universidad de las Islases Balleares, Spain

Dr. Claudia Gerber, (2002) University of Tübingen, Germany

Prof. Gabi Waite, (2008-2009), Indiana State University, USA

Finished thesis at CAR (PhD and MD)

1. Sabine Mütze, MD, 2005, Myeloperoxidase and IRP1, summa cum laude

2. Reiner Fritz, MD, 2009, Peroxisomaler H₂O₂-Stoffwechsel, magna cum laude

3. Susanne Hagist, MD, 2009, Genome-wide micro array of iron-relevant genes, magna cum laude

4. Julia Mangin, MD, Labile iron pool, 2011, magna cum laude

5. Steffi Adolf, MD, Liver stiffness and pregnancy, 2012, magna cum laude

6. Anna Kohlhaas, Liver stiffness and ascites, 2013, magna cum laude

7. Christian Dietrich, Liver stiffness and heart failure, 2014, cum laude

8. Ingo Ganzleben, graduate student (supervisor: Dr. Millonig), magna cum laude

9. Felix Piecha, graduate student, 2017, (2013-2017), Pharmacological modulation of liver stiffness in small animal models, magna cum laude 

10. Ines Silva, biologist, PhD student, Dr. sc. hum, 2020, (2017-2020), magna cum laude

11. Omar Elshaarawy, MD, (2018-2020), magna cum laude 

12. Hanna Raisi, MD clinical fellow, (2015-2020), cum laude 

13. Linna Yu, MD-PhD fellow, (2019-2022), iron modulation of hepcidin signaling, magna cum laude 

14. Shijin Wang, MD-PhD fellow, (2019-2022), BMP-mediated iron signaling, magna cum laude

15. Chen Cheng, PhD fellow, Dr. sc. hum.  (2019-2022), Modulation of autophagy by alcohol and peroxide, magna cum laude

16. Felix Englert, MD-PhD fellow, (2020-2025), Liver detoxification of microplastics,  magna cum laude

17. Chaowen Zheng, MD-PhD, (2022-2025), Direct red blood cell ingestion by hepatocytes (efferocytosis),  magna cum laude

18. Sijuan Li (2022-2025?), MD-PhD, Ethanol-mediated phosphatidylserine-dependent clearance of red blood cells by liver sinusoidal endothelial cells (efferocytosis)

19. Guoqing Ouyang, MD-PhD,  (2024-2026?),  Stage-dependent genetic effects explain inconsistent associations with mortality in alcohol-related liver disease

20.  Xiang Gao, MD-PhD fellow , (2023-2026?) (in cooperation with Prof. S. Immenschuh, Hannover) 

21. Yan Jin, MD-PhD fellow , (2023-2026?) (in cooperation with Prof. S. Immenschuh, Hannover)

Past and present cooperations

Iron studies:

Prof. K. Pantopoulos, McGill University, Montreal, Canada

Prof. S. Chokshi, Plymouth, UK

Prof. L. Devireddy, Case Western Reserve University, Cleveland, USA

Prof. M. Muckenthaler, Molcular Partnership Unit, Universität Heidelberg und EMBL

Prof. P. Strnad, Cottbus, Germany

Dr. B. Avrin, Insight Magnetics, San Diego, USA

b) Oxidative Stress und redox regulation

Prof. T. Dick, DKFZ, Heidelberg

Prof. E. Albano, University of Novara, Italien

c) Alcoholic liver cirrhosis, matrix biology

Prof. C. Wang, Nutrition Center, Boston, USA

Prof. H. Bantel, Medizinische Hochschule Hannover, Germany    

Prof. V. Vasilis, University of Colorado Denver, USA

Prof. T. Morgan, SCIRE and VA Long Beach Healthcare System, Los Angeles, USA

Prof. D. Seth, Centenary Institute & Royal Prince Alfred Hospital, Sydney, Australia

Prof. P.S: Haber, P.S. Centenary Institute & Royal Prince Alfred Hospital, Sydney, Australia

Prof. F. Stickel, University of Bern, Bern, Switzerland

Prof. C. Day, Freeman Hospital & Newcastle University, Newcastle upon Tyne, UK

Prof. M. Beaugrand, University of Paris, France

Prof. Andreas Nüssler, University of Tübingen, Germany

Prof. C. Lackner, University of Graz

c) Liver stiffness, non-invasive diagnosis

Prof. Trabut, Hôpitaux de Paris, France

Dr. L. Sandrin, Echosens, Paris, France

Prof. M. Beaugrand, University of Paris, France

Prof. M. Lupsor, CLuj, Romania

Dr. Yagmur, Stein Laboratory, Aachen, Germany